About Dr. Freeze and His Research
Dr. Freeze joined the faculty of the Sanford Burnham Prebys Medical Discovery Institute in 1988 and served as the Director of the Glycobiology and Carbohydrate Chemistry Program from 2000-2008. He is currently the Director of the Institute's Human Genetics Program. His work focuses on pathology resulting from faulty glycos-ylation, the process of adding sugar chains to proteins and lipids. Carbohydrates are required for proper secretion and targeting of thousands of proteins, an often overlooked fact of biology.
He is driven by the search for novel therapeutics to treat patients with mutations leading to glycosylation defects called Congenital Disorders of Glycosylation or CDGs. We invite you to learn about the children with CDGs, read their stories, and meet the researchers seeking a cure for their disorders.
Meet the Freeze Lab