| | Principal Investigator | | Evan Y. Snyder earned his M.D. and Ph.D. (in neuroscience) from the University of Pennsylvania in 1980 as a member of NIH's Medical Scientist Training Program (MSTP). (He had also studied psychology and linguistics at the University of Oxford). After moving to Boston in 1980, he completed residencies in pediatrics and neurology as well as a clinical fellowship in Neonatal-Perinatal Medicine at Children's Hospital-Boston, Harvard Medical School. He also served as Chief Resident in Medicine (1984-85) and Chief Resident in Neurology (1987) at Children's Hospital-Boston. In 1989, he became an attending physician in the Department of Pediatrics (Division of Newborn Medicine) and Department of Neurology at Children's Hospital-Boston, Harvard Medical School. From 1985-91, concurrent with his clinical activities, he conducted postdoctoral research as a fellow in the Department of Genetics, Harvard Medical School. In 1992, Dr. Snyder was appointed an instructor in neurology (neonatology) at Harvard Medical School and was promoted to assistant professor in 1996. He maintained lab spaces in both Children's Hospital-Boston and at Harvard Institutes of Medicine/Beth-Israel Deaconess Medical Center. In 2003, Dr. Snyder was recruited to the Burnham Institute for Medical Research as Professor and Director of the Program in Stem Cell & Regenerative Biology. He then inaugurated the Stem Cell Research Center (serving as its founding director) and initiated the Southern California Stem Cell Consortium. Dr. Snyder is a Fellow of the American Academy of Pediatrics (FAAP). He also received training in Philosophy and Linguistics at Oxford University | | | Postdoctoral Fellow | | Andrew completed his doctoral training in the UCSD School of Medicine Biomedical Sciences Program and is working on several projects in the lab and plays key roles in both industry and acedemic projects and collaborations. He previously identified a novel HMG box protein at the mitochondria that undergoes PTM that when disrupted, leads to neurodegeneration. Andrew is also involved in the Bipolar Disorder project where he is investigating neuronal targets of Lithium and target/cytoskeletal interactions. | | | Visiting Scientist | | Lane is a visiting scientist interested in the chemosensory control of stem cell homing to pathological sites. His approach is to examine pathology homing in the context of eukaryotic chemotaxis and haptotaxis with an emphasis on therapies for brain tumors. He is developing 3D model systems of this 'pathotropism' to aid detailed mechanistic studies of homing. He is testing a hypothesis that allosteric interactions within the receptors for the chemokines that mediate these tropisms underlie chemotactic adaptation as neural stem cells migrate to pathotropin sources and sensitize directional motility control to invasive brain tumor cells. He has Bachelors of Science degrees in Biology and Chemistry from the California Institute of Technology, a Doctor of Philosophy degree in the Neurosciences from the University of Wisconsin, and did postdoctoral work in biophysics at the Albert Einstein College of Medicine. He has held faculty positions at the Rush University Medical Center and the University of Illinois, and senior scientific investigator positions in industry at companies including Aurora Biosciences Corp., Genoptix, Biosite Diagnostics, and others. | | | Visiting Scientist | | Dr. Tobe is a visiting scientist currently investigating the epigenetic and phosphoproteomic differences in neural progeny from iPSC's derrived from human patients with psychiatric disorders such as bipolar and schizophrenia. | | | Postdoctoral Fellow | | Shreyasi Das joined as a postdoctoral fellow at the Sanford Burnham Medical Research Institute where she is part of the CIRM funded collaboration between the Snyder Laboratory and Mandala Biosciences. Previously, she was a postbaccalaureate fellow at the National Cancer Institute in the Carcinogen-DNA Interactions Section of the Laboratory of Cancer Biology and Genetics. She subsequently completed a Ph.D. in cancer biology at the University of Wisconsin-Madison, McArdle Laboratory for Cancer Research. Shreyasi aims to define unique cell surface antigens to isolate specific cell populations derived from differentiated human embryonic progenitor cell lines. | | | Research Technician | | | | | Graduate Student | | Induced human pluripotent stem cell -Disease in a Dish- models are providing novel insights into complicated diseases that were not previously attainable. Specifically, central nervous system disorders with intricate behavioral symptoms have proven difficult to study at the cellular and molecular level. Utilizing iPSC technologies, human cell cultures from affected patients can be generated that are representative and predictive of the pathology underlying their disease. Cameron is interested in utilizing these stem cell tools to elucidate how changes in the molecular biology of the brain results in complex changes in behavior and cognition. | | | Master's Student | | Anthony is a master's student in the UCSD Department of Biology working with the Snyder lab on a project in collaboration with the Center for Theoretical and Applied Neuro-Oncology at the UCSD Moores Cancer Center. | | | Undergraduate Intern | | | | | Visiting Researcher | | | | | Postdoctoral Fellow | | |
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| | | | | Research Fellow in Neurology-BIDMC | | | | | | Sr. Principal Scientist & Lab Head for Target Identification Pfizer Neuroscience, Cambridge, MA. | | | MGH Neurology | | | Postdoc, BIMR | | | Assistant Professor I.S.U. | | | BIDMC | | | Assistant Professor of Surgery- Children's Hospital Boston | | | M.I.T. | | | Instructor in Neurology- Harvard Medical School | | | | | | Scientist, International Stem Cell | | | Assistant Professor, Tulane | | | | | | | | | Assistant Professor I.S.U. | | | Neurosurgery Dept. Vancouver | | | | | | | | | | | | Neurosurgery, City of Hope, Duarte, CA | | | Postdoc, Jeff Kordower Lab, Rush Univ. | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Assistant Professor, VUB Belgium | | | | | | | | | |
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