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The Kaufman Lab
Sanford Burnham Prebys Medical Discovery Institute
Neuroscience and Aging Research Center
Lab Members
kaufman lab

Audrey Kapelanski-Lamoureux,Zhouji Chen, Zu-Hua Gao, Ruishu Deng, Anthoula Lazaris, Cynthia Lebeaupin, Lisa Giles, Jyoti Malhotra, Jing Yong, Chenhui Zou, Ype P. de Jong, Peter Metrakos, Roland W. Herzog, Randal J. Kaufman, December 7, 2022 Ectopic clotting factor VIII expression and misfolding in hepatocytes as a cause for hepatocellular carcinoma

Hung HH, Nagatsuka Y, Soldà T, Kodali VK, Iwabuchi K, Kamiguchi H, Kano K, Matsuo I, Ikeda K, Kaufman RJ, Molinari M, Greimel P, Hirabayashi Y. December 12, 2022. Selective involvement of UGGT variant: UGGT2 in protecting mouse embryonic fibroblasts from saturated lipid-induced ER stress.

Chen, Z., Wang, S., Pottekat, A., Duffey, A., Jang, I., Chang, B.H., Cho, J., Finck, B.N., Davidson, N.O., Kaufman, R.J. 2022. Conditional hepatocyte ablation of PDIA1 uncovers its indispensable roles for 1 both APOB and MTTP folding to support VLDL secretion. Revision to be submitted to Elife.

Arunagiri, A., Alam, M., Haataja, L., Sidarala, V., Samy, P., Sadique, N., Jang, I., Soleimanpour, S.A., Satin, L., Itkin-Ansari, P., Kaufman, R.J., Liu, M., Arvan. P. 2022. Detecting Proinsulin Misfolding in the Endoplasmic Reticulum. Submitted to Diabetes.

Tran, D., Pottekat, A., Lee, K., Raghunathan, M., Loguercio, S., Mir, S., Paton, A.W., Paton, J.C., Arvan, P., Kaufman, R.J., Itkin-Ansari, P. 2022. Inflammatory cytokines rewire the proinsulin interaction network in human islets bioRxiv 2022.04.07.487532; doi: https://doi.org/10.1101/2022.04.07.487532. Submitted to Diabetes.

Butterfield, J.S.S., Yamada, K., Bertolini, T.B., Syed, F., Kumar, S.R.P., Li, X., Arisa, S., Piñeros, A.R., Tapia, A., Rogers, C.A., Li, N., Rana, J., Biswas, M., Terhorst, C., Kaufman, R.J., de Jong, Y-P., Herzog, R.W. 2022. IL-15 Blockade Ameliorates Multifactorial Loss of Factor VIII Protein Production by AAV-Transduced Hepatocytes in Hemophilia A Mice. Molecular Therapy (In Press).

Peng, Y., Chen, Z., Jang, I., Arvan, P., Kaufman, R.J. 2020/bioRxiv 2020.01.01.892539; Epitope-tagging of the endogenous murine BiP/GRP78/Hspa5 locus allows direct analysis of the BiP interactome and protein misfolding in vivo. doi: https://doi.org/10.1101/2020.01.01.892539

Complete list of Kaufman Lab publications


The Kaufman Lab is located at:

Sanford Burnham Prebys Medical Discovery Institute
10901 North Torrey Pines Road
La Jolla, CA 92037

Please direct all lab-related inquiries to Alec Duffey

Please direct all research administrative inquiries to Lindsay Bazett