​About Dr. Freeze and​ His Research

Dr.  Freeze ​joined th​e faculty of  the  Sanford  Burnham Prebys Medical Discovery Institute  in  1988  and  served  as  the Director of the Glycobiology and  Carbohydrate Chemistry P​rogram from 2000-2008. He is cu​rrentl​​​y the Director of the Institute's Human Genetics Program. His work focuses on pathology resulting fr​om faulty glycos-​ylation, the process of adding sugar chains to proteins and lipids. Carbohydrates are required for proper secretion and targeting of thousands of proteins, an often overlooked fact of biology.




​He is drive​n by the search for novel therapeutics to treat patients with mutations leading to glycosylation defects called Congenital Disorders of Glycosylation or CDGs.  We invite you to learn about the children with CDGs, read their stories, and meet the researchers seeking a cure for their disorders.

Meet the Freeze Lab​


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