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ABOUT DR. FREEZE and HIS RESEARCH

Dr.  Freeze joined  the  faculty  at  the  Sanford  Burnham  Institute  in  1988  and  served  as  the Director of the Glycobiology and  Carbohydrate Chemistry Program  from 2000-2008. He is currently the Director of the Institute's Human Genetics program. His work focuses on pathology resulting from faulty glycosylation, the process of adding sugar chains to proteins  and  lipids. Carbohydrates are required for proper secretion and targeting of thousands of proteins an often overlooked fact of biology.

He is driven by the search for novel therapeutics to treat patients with mutations leading to glycosylation defects called Congenital Disorders of Glycosylation or CDGs.  We invite you to learn about the children with CDGs, read their stories, and meet the researchers seeking a cure for their disorders.

Meet the Freeze Lab