Dr. Freeze joined the faculty at the Sanford Burnham Institute in 1988 and served as the Director of the Glycobiology and Carbohydrate Chemistry Program from 2000-2008. His work focuses on pathology resulting from faulty glycosylation, the process of adding sugar chains to proteins and lipids. Carbohydrates are required for proper secretion and targeting of thousands of proteins an often overlooked fact of biology. He is driven by the search for novel therapeutics to treat patients with mutations leading to glycosylation defects called Congenital Disorders of Glycosylation or CDGs. We invite you to learn about the children with CDGs, read their stories, and meet the researchers seeking a cure for their disorders.